Abstract
The staphylococcal accessory regulator SarA and the alternative sigma factor sigma(B) have been previously identified as positive regulators, and IcaR as a negative regulator, of icaADBC expression. Here, we show that in Staphylococcus aureus SarA and sigma(B) are also required for icaR expression and that IcaR does not have a significant effect on its own expression.
Publication types
-
Research Support, N.I.H., Extramural
MeSH terms
-
Adhesins, Bacterial / genetics*
-
Adhesins, Bacterial / metabolism
-
Adhesins, Bacterial / physiology
-
Bacterial Proteins / genetics*
-
Bacterial Proteins / metabolism
-
Biofilms / growth & development
-
Gene Expression Regulation, Bacterial*
-
Genetic Complementation Test
-
Models, Biological
-
Mutation
-
Promoter Regions, Genetic / genetics
-
Sigma Factor / genetics
-
Sigma Factor / metabolism
-
Staphylococcus aureus / genetics*
-
Staphylococcus aureus / metabolism
-
Staphylococcus aureus / physiology
-
Trans-Activators / genetics
-
Trans-Activators / metabolism
Substances
-
Adhesins, Bacterial
-
Bacterial Proteins
-
SarA protein, bacterial
-
Sigma Factor
-
Trans-Activators