Abstract
Fourty patients with thyroid nodules were examined. Benchmarking study of FNA results, histology reports and immunohistochemistry of Galectin-3 expression were performed. Galectin-3 is a highly sensitive oncomarker for papillary carcinoma of thyroid gland: sensitivity--100%, specificity--71%, diagnostic value--85%.
MeSH terms
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Adult
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Aged
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Biomarkers, Tumor / biosynthesis*
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Biopsy, Fine-Needle
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Carcinoma, Papillary / metabolism*
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Carcinoma, Papillary / pathology*
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Galectin 3 / biosynthesis*
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Humans
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Male
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Middle Aged
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Sensitivity and Specificity
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Thyroid Neoplasms / metabolism*
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Thyroid Neoplasms / pathology*
Substances
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Biomarkers, Tumor
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Galectin 3