A small molecule CXCR4 antagonist inhibits neointima formation and smooth muscle progenitor cell mobilization after arterial injury

J Thromb Haemost. 2008 Oct;6(10):1812-5. doi: 10.1111/j.1538-7836.2008.03086.x. Epub 2008 Jul 19.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Arteries / injuries*
  • Cell Movement / drug effects*
  • Coronary Restenosis / prevention & control
  • Mice
  • Muscle, Smooth, Vascular / cytology
  • Pyridines / pharmacology*
  • Receptors, CXCR4 / antagonists & inhibitors*
  • Stem Cells / physiology
  • Stents / adverse effects
  • Tunica Intima / drug effects*
  • Tunica Intima / growth & development

Substances

  • N-(1,4,8,11- tetraazacyclotetradecanyl-1,4-phenylenebis(methylene))-2-(aminomethyl)- pyridine
  • Pyridines
  • Receptors, CXCR4