Abstract
Antibacterial and antifungal activity of 2,4-dihydro- [1,2,4]triazol-3-one derivatives were examined by the disc-diffusion method (growth inhibition zone diameter in agar medium). The MIC's for the most active agents were determined. Of all the tested compounds, aminomethyl derivatives of 2,4-dihydro-[1,2,4]triazol-3-one exhibit activity against the majority of microorganisms studied.
MeSH terms
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / pharmacology*
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Antifungal Agents / chemistry
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Antifungal Agents / pharmacology*
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Disk Diffusion Antimicrobial Tests
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Gram-Negative Bacteria / drug effects*
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Gram-Positive Bacteria / drug effects*
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Triazoles / chemistry
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Triazoles / pharmacology*
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Yeasts / drug effects*
Substances
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Anti-Bacterial Agents
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Antifungal Agents
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Triazoles