Abstract
Continuing efforts to establish a more general "user-friendly" protocol for the palladium-catalysed arylation of amines (Buchwald-Hartwig reaction) are described herein. Significant advances have been made through the use of the versatile (SIPr)Pd(methallyl)Cl complex in conjunction with the reliable base lithium hexamethyldisilazide (LHMDS).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amines / chemistry*
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Benzene Derivatives / chemistry*
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Catalysis
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Molecular Structure
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Morpholines / chemistry
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Organometallic Compounds / chemical synthesis
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Organometallic Compounds / chemistry*
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Palladium / chemistry*
Substances
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Amines
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Benzene Derivatives
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Morpholines
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Organometallic Compounds
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Palladium
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morpholine