Abstract
Fonsecaea pedrosoi is the most prevalent aetiological agent of chromoblastomycosis. Fonsecaea monophora is a new species segregated from Fonsecaea pedrosoi. Herein, we report on three cases of chromoblastomycosis caused by F. monophora that were successfully treated with terbinafine and/or itraconazole. Clinical characteristics and mycological parameters are described. Two of the three patients underwent combination therapy with itraconazole and terbinafine during early stages of treatment and were completely healed in a relatively short course of treatment.
MeSH terms
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Adult
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Antifungal Agents* / administration & dosage
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Antifungal Agents* / therapeutic use
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Ascomycota / classification
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Ascomycota / drug effects*
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Ascomycota / isolation & purification
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China
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Chromoblastomycosis / drug therapy*
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Chromoblastomycosis / microbiology
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Chromoblastomycosis / pathology
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Drug Therapy, Combination
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Face / microbiology
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Face / pathology
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Humans
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Itraconazole* / administration & dosage
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Itraconazole* / therapeutic use
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Leg Dermatoses / drug therapy*
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Leg Dermatoses / microbiology
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Leg Dermatoses / pathology
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Male
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Middle Aged
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Naphthalenes* / administration & dosage
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Naphthalenes* / therapeutic use
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Terbinafine
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Treatment Outcome
Substances
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Antifungal Agents
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Naphthalenes
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Itraconazole
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Terbinafine