[Synchronous squamous vulvar and cervical cancer--a case report with literature review and analysis of therapeutic strategies]

Przegl Lek. 2008;65(3):153-6.
[Article in Polish]

Abstract

We report on a suboptimal surgical treated cancer of the vulva with the accidental diagnosis of a second cancer within the completion of the surgery three weeks later. The patient was 48 years old, presenting with a central, multifocal, exophytic tumor of the clitoris. The primary surgery was: vulvectomy with bilateral inguinal lymphadenectomy ("triple incision"). However, the pathological examination revealed an unsatisfactory surgical result--on the one site (laterally) the tumor reached the resection edge, and on the other site (dorsally) the tumor-free margin was only 1-2 mm. There were 5 nodal metastases--4 ipsilateral (one macrometastasis), and 1-contralateral. The next step was total abdominal hysterectomy (co-existing 10cm myoma) and pelvic lymph node sampling (on both sites negative). We discuss two problems in light of the current literature: the preoperative therapy planning of advanced vulvar cancer (exenteration vs. neoadjuvant chemotherapy with subsequent radical vulvectomy, triple incision vs. en bloc resection, pelvic lymphadenectomy) and the importance of a careful evaluation of the cervix in each case of vulvar cancer--the coincidence of both tumor localizations is up to 7-10%. The diagnosis of the second cancer probably remains in many cases delayed.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Carcinoma, Squamous Cell / surgery*
  • Female
  • Humans
  • Middle Aged
  • Neoplasms, Second Primary / surgery*
  • Uterine Cervical Neoplasms / surgery*
  • Vulvar Neoplasms / surgery*