Light sources for photodynamic inactivation of bacteria

Lasers Med Sci. 2009 May;24(3):453-60. doi: 10.1007/s10103-008-0588-5. Epub 2008 Jul 12.

Abstract

Bacteria have an important role in human and animal morbidity, and a great number of them have developed antibiotic resistance. In the past recent years a new way of dealing with this problem has been studied: photodynamic inactivation. This method is based on administration of a photosensitizing substance that fixes itself in the bacterial cell followed by exposure to a light source. In the experiments done by many researchers on photodynamic inactivation of bacteria, both coherent and non-coherent light sources were used. This article is a review of these light sources and of some experimental results obtained by different authors.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Bacteria / pathogenicity
  • Bacteria / radiation effects*
  • Humans
  • In Vitro Techniques
  • Lasers
  • Light
  • Optical Phenomena
  • Photobiology
  • Photochemotherapy
  • Photosensitizing Agents

Substances

  • Photosensitizing Agents