Electroencephalographic evaluation of gold wire implants inserted in acupuncture points in dogs with epileptic seizures

Res Vet Sci. 2009 Feb;86(1):152-61. doi: 10.1016/j.rvsc.2008.05.019. Epub 2008 Jul 14.

Abstract

The purpose of this study was to evaluate both, clinically and with electroencephalographic (EEG) recordings, the effect of gold wire implants in acupuncture points in dogs with uncontrolled idiopathic epileptic seizures. Fifteen dogs with such diagnosis were enrolled in the study. A first EEG recording was performed in all dogs under anaesthesia with xylazine (1mg/kg) and propofol (6 mg/kg) before the treatment protocol, and a second EEG was performed 15 weeks later. Relative frequency power, intrahemispheric coherence available through EEG, number of seizures and seizure severity were compared before and after treatment using a Wilcoxon signed-rank test. There were no significant statistical differences before and after treatment in relative power or in intrahemispheric coherence in the EEG recording. However, there was a significant mean difference in seizure frequency and seizure severity between control and treatment periods. After treatment, nine of the 15 dogs (60%) had at least a 50% reduction in seizures frequency during the 15 weeks established as follow-up of this treatment.

MeSH terms

  • Acupuncture Therapy / methods
  • Acupuncture Therapy / standards
  • Acupuncture Therapy / veterinary*
  • Animals
  • Dog Diseases / diagnosis
  • Dog Diseases / physiopathology
  • Dog Diseases / therapy*
  • Dogs
  • Electroencephalography / veterinary
  • Epilepsies, Myoclonic / diagnosis
  • Epilepsies, Myoclonic / physiopathology
  • Epilepsies, Myoclonic / therapy
  • Epilepsies, Myoclonic / veterinary*
  • Female
  • Gold / therapeutic use*
  • Male
  • Seizures / diagnosis
  • Seizures / physiopathology
  • Seizures / therapy
  • Seizures / veterinary*

Substances

  • Gold