[Study on anti-diabetes active fraction and constituents from Potentilla chinesis]

Zhongguo Zhong Yao Za Zhi. 2008 Mar;33(6):680-2.
[Article in Chinese]

Abstract

Objective: To study the active fraction and constituents from Potentilla chinesis.

Method: Tested fractions were obtained by different solvent-partition from 95% ethanol-extracts of P. chinesis, and tested compound was isolated by repeated chromatography. Anti-diabetes experiment was taken by using alloxan-induced diabetic mice.

Result: The fraction F and the tested compound revealed obvious difference comparing with the control group (P <0.01).

Conclusion: Fraction F and potentilla flavone revealed the significant hypoglycemic effect in alloxan-induced diabetic mice.

MeSH terms

  • Animals
  • Blood Glucose / metabolism
  • Diabetes Mellitus, Experimental / blood
  • Diabetes Mellitus, Experimental / drug therapy*
  • Drugs, Chinese Herbal / chemistry*
  • Drugs, Chinese Herbal / pharmacology*
  • Drugs, Chinese Herbal / therapeutic use
  • Female
  • Flavones
  • Flavonoids / pharmacology
  • Hypoglycemic Agents / chemistry*
  • Hypoglycemic Agents / pharmacology*
  • Hypoglycemic Agents / therapeutic use
  • Male
  • Mice
  • Potentilla / chemistry*

Substances

  • Blood Glucose
  • Drugs, Chinese Herbal
  • Flavones
  • Flavonoids
  • Hypoglycemic Agents
  • flavone