Relationship between clinical, 24-hour, average day-time and night-time blood pressure and measures of arterial stiffness in essential hypertension

Physiol Res. 2008;57(2):303-306. doi: 10.33549/physiolres.931446.

Abstract

Arterial wall stiffness is considered an independent cardiovascular risk factor. Aim of this study was to evaluate relationship between clinical, 24-hour, average day-time and night-time blood pressure (BP) and measures of arterial stiffness assessed by pulse wave velocity (PWV) (using SphygmoCor applanation tonometer) in essential hypertension (severe-resistant (RH, n=29) and moderate hypertension (EH, n=35)) and in normotensive control subjects (n-29) (NCS) matched by age. After multiple regression analysis, PWV remains significantly correlated mainly with night-time pulse pressure and to a lesser extent with age. PWV was significantly higher in RH compared to moderate EH and NCS.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Arteries / physiology
  • Arteries / physiopathology*
  • Blood Pressure / physiology*
  • Case-Control Studies
  • Circadian Rhythm / physiology*
  • Elasticity
  • Hemodynamics
  • Humans
  • Hypertension / physiopathology*
  • Middle Aged
  • Muscle Relaxation / physiology
  • Muscle, Smooth, Vascular / physiology*
  • Muscle, Smooth, Vascular / physiopathology
  • Pulsatile Flow / physiology
  • Reference Values