Pseudo-hypopyon as the presenting feature of recurrent B-cell lymphoma

Ocul Immunol Inflamm. 2008 May-Jun;16(3):121-2. doi: 10.1080/09273940802026052.

Abstract

Purpose: To report a case of a pseudo-hypopyon as the presentation for recurrent B-cell lymphoma.

Design: Case report.

Methods: Case report with anterior segment photograph.

Results: A 74-year-old man with past medical history of peripheral B-cell lymphoma developed a hypopyon 3 months after R-CHOP chemotherapy and prophylactic intrathecal chemotherapy. Anterior chamber aspirate was consistent with B-cell lymphoma.

Conclusions: Pseudo-hypopyon as a manifestation of recurrent B-cell lymphoma is a rare clinical presentation of an intraocular malignancy. A high index of suspicion along with intraocular fluid analysis are essential to establish the diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anterior Chamber* / pathology
  • Anterior Eye Segment / pathology
  • Antibodies, Monoclonal / therapeutic use
  • Antibodies, Monoclonal, Murine-Derived
  • Antimetabolites, Antineoplastic / administration & dosage
  • Antimetabolites, Antineoplastic / therapeutic use
  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / therapeutic use
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Aqueous Humor / cytology
  • Cyclophosphamide / therapeutic use
  • Doxorubicin / therapeutic use
  • Eye Diseases / etiology*
  • Eye Diseases / pathology
  • Humans
  • Injections, Spinal
  • Lymphoma, B-Cell / complications*
  • Lymphoma, B-Cell / drug therapy
  • Lymphoma, B-Cell / pathology
  • Male
  • Neoplasm Recurrence, Local / prevention & control
  • Neoplasm Staging
  • Prednisolone / therapeutic use
  • Rituximab
  • Suppuration
  • Vincristine / therapeutic use

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Murine-Derived
  • Antimetabolites, Antineoplastic
  • Antineoplastic Agents
  • Rituximab
  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Prednisolone

Supplementary concepts

  • VAP-cyclo protocol