Homeostasis model assessment-insulin resistance (HOMA-IR), a key role for assessing the ovulation function in polycystic ovary syndrome (PCOS) patients with insulin resistance

Endocr J. 2008 Oct;55(5):943-5. doi: 10.1507/endocrj.k08e-094. Epub 2008 Jun 14.

Abstract

According to our research, we evaluated that for the ovulation function in polycystic ovary syndrome (PCOS) with IR, Homeostasis model assessment-insulin resistance (HOMA-IR) is a clinic , simple and practical and sensitive Index for assessing the ovualtion failure. Meanwhile, after anti-IR treatment, HOMA-IR is also a reliable and simple for accessing the recoverying ovulation function.

MeSH terms

  • Cyproterone Acetate / therapeutic use
  • Drug Combinations
  • Ethinyl Estradiol / therapeutic use
  • Female
  • Homeostasis*
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Insulin Resistance*
  • Metformin / therapeutic use
  • Models, Biological
  • Ovarian Follicle / pathology
  • Ovary / physiopathology
  • Ovulation*
  • Polycystic Ovary Syndrome / drug therapy
  • Polycystic Ovary Syndrome / pathology
  • Polycystic Ovary Syndrome / physiopathology*
  • Sensitivity and Specificity

Substances

  • Drug Combinations
  • Hypoglycemic Agents
  • Ethinyl Estradiol
  • Cyproterone Acetate
  • Cyproterone acetate, ethinyl estradiol drug combination
  • Metformin