Nanoscale depth resolution in scanning near-field infrared microscopy

Opt Express. 2008 May 12;16(10):7453-9. doi: 10.1364/oe.16.007453.

Abstract

We have recorded nanoscale topography and infrared chemical fingerprints of attomole layered lipids consisting of dimyristoylpho-sphatidylcholine on silicon and mica. Lipids deposited on mica built stacks consisting of up to 25 bilayers, each approximately 5 nm thick, spanning a range from 5-125 nm in height. Contrast evaluation as a function of layer thickness provides the near-field depth resolution.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aluminum Silicates / chemistry
  • Cell Membrane / metabolism
  • Dimyristoylphosphatidylcholine / chemistry
  • Equipment Design
  • Lipid Bilayers / chemistry*
  • Microscopy / methods*
  • Microscopy, Atomic Force / methods
  • Nanoparticles / chemistry
  • Nanostructures / chemistry
  • Nanotechnology / methods*
  • Optics and Photonics*
  • Silicon / chemistry
  • Spectroscopy, Near-Infrared / methods*

Substances

  • Aluminum Silicates
  • Lipid Bilayers
  • Dimyristoylphosphatidylcholine
  • mica
  • Silicon