A measurement technique for evaluation of processes occurring in the myocardium during blood flow arrest is presented. The system is devoted to monitoring the myocardium state during off-pump coronary artery by-pass grafting, i.e. during a surgical operation performed on a beating heart. A substantial part of the system is a probe whose construction is similar to a mechanical stabilizer. Such a stabilizer is used for preventing the myocardium from moving, thus it enables stitching of the graft and artery. In comparison to the commercially available stabilizer the developed probe is enhanced with a set of electrodes. These electrodes enable simultaneous measurements of impedance and electrograms. Examples of recordings made during in vivo studies are also presented. Thus, the proposed method is applicable and potentially very useful in clinical practice.