Abstract
The Casimiroa pringlei essential oil was analyzed to determine its chemical composition. Its effect on rat uterine smooth muscle was studied and compared with verapamil. Pure commercial piperitone, eucalyptol, and alpha-terpineol, the major constituents of C. pringlei essential oil, were tested on the uterine tonic contraction induced by high-potassium depolarizing solution (KCl 60 mM).
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Analysis of Variance
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Animals
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Calcium Channel Blockers / pharmacology
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Casimiroa* / chemistry
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Chromatography, Gas
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Female
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Mass Spectrometry
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Oils, Volatile / chemistry
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Oils, Volatile / isolation & purification
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Oils, Volatile / pharmacology*
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Parasympatholytics / chemistry
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Parasympatholytics / isolation & purification
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Parasympatholytics / pharmacology*
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Plant Extracts
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Plant Oils / chemistry
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Plant Oils / isolation & purification
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Plant Oils / pharmacology
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Potassium Chloride / pharmacology
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Rats
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Uterine Contraction / drug effects*
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Uterus / drug effects*
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Verapamil / pharmacology
Substances
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Calcium Channel Blockers
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Oils, Volatile
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Parasympatholytics
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Plant Extracts
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Plant Oils
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Potassium Chloride
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Verapamil