Predicting key long-range interaction sites by B-factors

Peng Chen; Kyungsook Han; Xueling Li; De-Shuang Huang

doi:10.2174/092986608784567573

Predicting key long-range interaction sites by B-factors

Protein Pept Lett. 2008;15(5):478-83. doi: 10.2174/092986608784567573.

Authors

Peng Chen¹, Kyungsook Han, Xueling Li, De-Shuang Huang

Affiliation

¹ Hefei Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei Anhui, 230031, China.

PMID: 18537737
DOI: 10.2174/092986608784567573

Abstract

In this paper, we adopted the bounded support vector machine to locate the key long-range interaction sites by the use of predicted local lowest B-factors. As a result, the key long-range interaction residues can be located based on information of local lowest B-factor sites.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Algorithms*
Computational Biology / methods*
Databases, Protein
Models, Molecular
Neural Networks, Computer
Protein Conformation
Protein Folding
Protein Interaction Domains and Motifs*
Protein Interaction Mapping*
Proteins / chemistry*
Temperature

Substances

Proteins