Synthesis of highly pure oxyphytosterols and (oxy)phytosterol esters. Part II. (Oxy)-sitosterol esters derived from oleic acid and from 9,10-dihydroxystearic acid [1]

Diane Julien-David; Philippe Geoffroy; Eric Marchioni; Françis Raul; Dalal Aoudé-Werner; Michel Miesch

doi:10.1016/j.steroids.2008.04.010

Synthesis of highly pure oxyphytosterols and (oxy)phytosterol esters. Part II. (Oxy)-sitosterol esters derived from oleic acid and from 9,10-dihydroxystearic acid [1]

Steroids. 2008 Oct;73(11):1098-109. doi: 10.1016/j.steroids.2008.04.010. Epub 2008 Apr 29.

Authors

Diane Julien-David¹, Philippe Geoffroy, Eric Marchioni, Françis Raul, Dalal Aoudé-Werner, Michel Miesch

Affiliation

¹ IPHC, UMR 7178, Laboratoire de Chimie Analytique et Sciences de l'Aliment-Université Louis Pasteur, Faculté de Pharmacie 74, route du Rhin, 67401 Strasbourg-Cedex, France.

PMID: 18533216
DOI: 10.1016/j.steroids.2008.04.010

Abstract

Several efficient synthetic routes giving readily access to (oxy)-sitosterol esters and (oxy)-cholesterol esters derived respectively from oleic acid and from 9,10-dihydroxystearic acid were developed for the first time. This approach allowed that sufficient amounts of the latter were available in order to carry out further biological studies.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Esterification
Esters / chemical synthesis*
Esters / chemistry
Molecular Structure
Oleic Acid / chemistry*
Phytosterols / chemical synthesis*
Phytosterols / chemistry
Phytosterols / isolation & purification
Sitosterols / chemical synthesis*
Sitosterols / chemistry
Stearic Acids / chemistry*

Substances

Esters
Phytosterols
Sitosterols
Stearic Acids
Oleic Acid