Abstract
A new simple method for the synthesis of alpha-glycosyl thiols is described. Ring-opening of 1,6-anhydrosugars with commercially available bis(trimethylsilyl)sulfide under the action of catalytic amounts of TMSOTf smoothly afforded alpha-glycosyl thiols in very high yields and in a stereospecific way.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Catalysis
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Mesylates / chemistry
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Stereoisomerism
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Sulfhydryl Compounds / chemical synthesis*
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Trimethylsilyl Compounds / chemistry
Substances
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Mesylates
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Sulfhydryl Compounds
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Trimethylsilyl Compounds
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trimethylsilyl trifluoromethanesulfonate