Abstract
DNA replication is fundamental to the propagation of cellular life. Remarkably, the bacterial replication machinery is distinct from that used by archaea and eukaryotes. In this article, we discuss the role that lateral gene transfer by extra-chromosomal elements might have had in shaping the replication machinery and even modulating the manner in which host cellular genomes are replicated.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Archaeal Proteins / classification
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Archaeal Proteins / genetics
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Archaeal Proteins / metabolism
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Bacterial Proteins / classification
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism
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Biological Evolution*
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Chromosomes / genetics*
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DNA Replication*
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Eukaryotic Cells / physiology
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Evolution, Molecular
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Gene Transfer, Horizontal / genetics*
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Multigene Family
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Phylogeny
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Replication Origin
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Replicon
Substances
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Archaeal Proteins
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Bacterial Proteins