Patient-tailored implantable cardioverter defibrillator testing using the upper limit of vulnerability: the TULIP protocol

Europace. 2008 Aug;10(8):907-13. doi: 10.1093/europace/eun136. Epub 2008 May 30.

Abstract

Aims: We evaluated the feasibility of the TULIP (Threshold test using Upper Limit during ImPlantation) protocol, which was designed to provide a confirmed, low defibrillation energy value during implantable cardioverter defibrillator (ICD) implantation with only two induced ventricular fibrillation (VF) episodes.

Methods and results: Ninety-eight patients (62 +/- 12 years, 86 male) from 13 clinical centres underwent an active can ICD implantation. A single coupling interval derived from electrocardiogram lead II during ventricular pacing was used for VF induction shocks at 13, 11, 9, and 6 J in a step-down manner until the upper limit of VF induction (ULVI) was determined. If ULVI >or=9 J, a defibrillation energy of ULVI + 4 J was tested. For ULVI <9 J, the defibrillation test energy was 9 J. In 79/98 patients (80.6%), two induced VF episodes were sufficient to obtain confirmed defibrillation energy of 11.1 +/- 3.3 J. The mean strength of the successful VF induction shock was 6.8 +/- 4.3 J, the coupling interval was 303 +/- 35 ms, and the number of delivered induction shocks until the first VF induction was 3.9 +/- 1.6.

Conclusion: TULIP is a safe and simple device testing procedure allowing the determination of confirmed, low defibrillation energy in most patients with two VF episodes induced at a single coupling interval.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Defibrillators, Implantable*
  • Equipment Design
  • Equipment Failure Analysis / methods*
  • Feasibility Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Therapy, Computer-Assisted / methods*
  • Treatment Outcome
  • Ventricular Fibrillation / rehabilitation*