Routine applications of DNA fingerprinting with the oligonucleotide probe (CAC)5/(GTG)5

H Neitzel; M Digweed; P Nürnberg; A Pöpperl; C A Schmidt; S Tinschert; K Sperling

doi:10.1111/j.1399-0004.1991.tb02994.x

Routine applications of DNA fingerprinting with the oligonucleotide probe (CAC)5/(GTG)5

Clin Genet. 1991 Feb;39(2):97-103. doi: 10.1111/j.1399-0004.1991.tb02994.x.

Authors

H Neitzel¹, M Digweed, P Nürnberg, A Pöpperl, C A Schmidt, S Tinschert, K Sperling

Affiliation

¹ Institut für Humangenetik, Universitätsklinikum Rudolf Virchow, Berlin, Germany.

PMID: 1849805
DOI: 10.1111/j.1399-0004.1991.tb02994.x

Abstract

The use of DNA fingerprinting with synthetic oligonucleotides is illustrated for practical applications familiar in clinical diagnostics: pre- and postnatal zygosity determination and the monitoring of bone marrow transplantation. A simple method for non-radioactive detection is described which may be interesting for many diagnostic laboratories.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Bone Marrow Transplantation
Child
DNA
DNA Fingerprinting / instrumentation
DNA Fingerprinting / methods*
DNA Restriction Enzymes
Female
Histocompatibility Testing / methods
Humans
Male
Nucleic Acid Hybridization
Oligonucleotide Probes*
Pregnancy
Prenatal Diagnosis / methods
Twins / genetics

Substances

Oligonucleotide Probes
DNA
DNA Restriction Enzymes