Abstract
The IMP-4 metallo-beta-lactamase, originally recognized in Acinetobacter spp. from Hong Kong, more recently appeared simultaneously in isolates of the family Enterobacteriaceae from Sydney and Melbourne, Australia. The bla(IMP-4)-qacG2-aacA4-catB3 cassette array was found in isolates from both cities, but in different wider genetic contexts and on different plasmids, suggesting movement of this array by homologous recombination.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Australia
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Bacterial Proteins / genetics*
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Enterobacteriaceae / enzymology
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Enterobacteriaceae / genetics*
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Enterobacteriaceae / isolation & purification
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Enterobacteriaceae Infections / microbiology
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Humans
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Molecular Sequence Data
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Polymerase Chain Reaction
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Sequence Analysis, DNA
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beta-Lactamases / genetics*
Substances
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Bacterial Proteins
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beta-lactamase IMP-4
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beta-Lactamases