qpcR: an R package for sigmoidal model selection in quantitative real-time polymerase chain reaction analysis

Bioinformatics. 2008 Jul 1;24(13):1549-51. doi: 10.1093/bioinformatics/btn227. Epub 2008 May 14.

Abstract

The qpcR library is an add-on to the free R statistical environment performing sigmoidal model selection in real-time quantitative polymerase chain reaction (PCR) data analysis. Additionally, the package implements the most commonly used algorithms for real-time PCR data analysis and is capable of extensive statistical comparison for the selection and evaluation of the different models based on several measures of goodness of fit.

Availability: www.dr-spiess.de/qpcR.html.

Supplementary information: Statistical evaluations of the implemented methods can be found at www.dr-spiess.de under 'Supplemental Data'.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Computer Simulation
  • Data Interpretation, Statistical
  • Gene Expression Profiling / methods*
  • Models, Genetic*
  • Models, Statistical
  • Programming Languages*
  • Reverse Transcriptase Polymerase Chain Reaction / methods*
  • Software*