Phenylenediamine catalysis of "click glycosylations" in water: practical and direct access to unprotected neoglycoconjugates

Org Biomol Chem. 2008 Jun 7;6(11):1898-901. doi: 10.1039/b805528a. Epub 2008 Apr 24.

Abstract

Phenylenediamine-catalyzed click chemistry leads to the efficient, practical, and column-free preparation of neoglycoconjugates from unprotected glucosyl azide, in pure water when aglycon solubility permits.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbohydrate Sequence
  • Catalysis
  • Glycoconjugates / chemistry*
  • Glycosylation
  • Magnetic Resonance Spectroscopy
  • Phenylenediamines / chemistry*
  • Water / chemistry

Substances

  • Glycoconjugates
  • Phenylenediamines
  • Water