Surgery of vagal paragangliomas: six patients and review of literature

Surg Oncol. 2008 Dec;17(4):281-7. doi: 10.1016/j.suronc.2008.03.001. Epub 2008 May 13.

Abstract

Background and aims: Vagal paragangliomas (VPs) represent a rare pathology in which surgery is usually recommended, but where experience is crucial to reduce the number of post-operative complications. In this study, we present our experience and a review of the literature.

Methods: Between 1991 and 2006 we have treated 42 patients with 50 paragangliomas of the head and neck (26 carotid, 18 jugular/tympanic and 6 vagal). Examination of the literature (Medline and non-indexed Spanish source) from the last 30 years has revealed 23 series that each reported more than three cases; reaching a total of 332 VPs.

Results: VPs are infrequent among paragangliomas of the head and neck (6/50) presenting clinical peculiarities such as multiple tumours, and malignant evolution. Within this current series, surgery was possible in all cases. Post-operative dysfunction in cranial nerves was frequent (the cranial X nerve was systematically sacrificed). There were no bronco-aspirations or mortalities. The literature review reveals similar results.

Conclusion: To obtain the best results, it is important that the candidates for surgery be selected by experts within multidisciplinary groups.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Angiography, Digital Subtraction
  • Cranial Nerve Neoplasms / diagnosis
  • Cranial Nerve Neoplasms / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neurosurgical Procedures / methods*
  • Paraganglioma / diagnosis
  • Paraganglioma / surgery*
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Vagus Nerve Diseases / diagnosis
  • Vagus Nerve Diseases / surgery*