Surveillance of antimicrobial resistance of Salmonella enterica serotype Typhi in seven Asian countries

C-H Chuang; L-H Su; J Perera; C Carlos; B H Tan; G Kumarasinghe; T So; P H VAN; A Chongthaleong; P-R Hsueh; J-W Liu; J-H Song; C-H Chiu

doi:10.1017/S0950268808000745

Surveillance of antimicrobial resistance of Salmonella enterica serotype Typhi in seven Asian countries

Epidemiol Infect. 2009 Feb;137(2):266-9. doi: 10.1017/S0950268808000745. Epub 2008 May 12.

Authors

C-H Chuang¹, L-H Su, J Perera, C Carlos, B H Tan, G Kumarasinghe, T So, P H VAN, A Chongthaleong, P-R Hsueh, J-W Liu, J-H Song, C-H Chiu

Affiliation

¹ Chang Gung Children's Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan.

PMID: 18474127
DOI: 10.1017/S0950268808000745

Abstract

Two hundred and four Salmonella enterica serotype Typhi (S. Typhi) isolates were collected from seven Asian countries during 2002-2004. Multidrug-resistant S. Typhi (resistant to > or = 3 antibiotics) was detected in 84 (41.2%) isolates and 142 (69.6%) showed reduced susceptibility to ciprofloxacin (minimum inhibitory concentration=0.125-1.0 mg/l). This study highlights the worsening situation of antimicrobial resistance of S. Typhi in Asia.

MeSH terms

Anti-Bacterial Agents / pharmacology*
Asia
Drug Resistance, Multiple, Bacterial*
Humans
Microbial Sensitivity Tests
Salmonella typhi / drug effects*
Salmonella typhi / isolation & purification
Typhoid Fever / microbiology*

Substances

Anti-Bacterial Agents