Abstract
Novel asymmetric 2-furyl additions of (2-furyl)AlEt(2)(THF) to aromatic ketones and one alpha,beta-unsaturated ketone catalyzed by a titanium catalyst of 10-20 mol% (S)-BINOL are reported to furnish tertiary furyl alcohols in good to excellent enantioselectivities of 87-93% ee.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alcohols / chemical synthesis*
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Alcohols / chemistry
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Aluminum / chemistry*
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Catalysis
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Furans / chemical synthesis*
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Furans / chemistry
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Ketones / chemistry*
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Naphthols / chemistry*
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Organometallic Compounds / chemistry*
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Stereoisomerism
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Titanium / chemistry*
Substances
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Alcohols
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BINOL, naphthol
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Furans
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Ketones
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Naphthols
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Organometallic Compounds
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Aluminum
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Titanium