[The results of treatment patients with hepatorenal syndrome. The analysis of 65 cases]

Pol Arch Med Wewn. 2006 Mar;115(3):227-33.
[Article in Polish]

Abstract

We analysed medical documentation of 65 patients with alcoholic cirrhosis admitted to the Internal Diseases Department with Dialysis Ward in the hospital in Wolomin between 2002 and 2004 year. Patients were divided into 3 groups according to renal disfunction: patients with HRS-1, patients with HRS-2 and patients with cirrhosis without renal failure. Each diagnosis was established basing on criteria of International Ascites Club. Different factors, which may influence a development of HRS, such as large--volume paracentesis without plasma expansion, bacterial infections, gastrointestinal bleeding and nephrotoxic drugs were analysed. Patients were treated with terlipressin and intravenous albumin infusions, antibiotics, diuretics, dopamine, haemodialysis and paracentesis. 10 patients (3 with HRS-1.5 with HRS-2 and 2 without renal failure) died, which is 15.4% of the all group. The mortality in the group of patients with HRS is high but complex treatment may be effective. Nowadays liver transplantation is the most effective method.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Albumins / therapeutic use
  • Diuretics / therapeutic use
  • Dopamine / therapeutic use
  • Female
  • Hepatorenal Syndrome / mortality*
  • Hepatorenal Syndrome / therapy*
  • Humans
  • Lypressin / analogs & derivatives
  • Lypressin / therapeutic use
  • Male
  • Middle Aged
  • Paracentesis
  • Renal Dialysis
  • Terlipressin
  • Treatment Outcome

Substances

  • Albumins
  • Diuretics
  • Lypressin
  • Terlipressin
  • Dopamine