Anhedonia and amotivation in psychiatric outpatients with fully remitted stimulant use disorder

Am J Addict. 2008 May-Jun;17(3):218-23. doi: 10.1080/10550490802019774.

Abstract

This study evaluated whether psychiatric outpatients with a past stimulant use disorder in full remission for >/= 2 months (STIM+, n = 204) and those with no history of stimulant use disorder (STIM-, n = 2070) differed in the prevalence of current anhedonia and amotivation. Results showed that a significantly greater proportion of STIM+ participants reported anhedonia and amotivation than STIM- participants. The relation between stimulant use disorder history and anhedonia remained robust after controlling for other relevant clinical and demographic factors. These findings suggest that anhedonia may be a preexisting risk factor or protracted effect of stimulant misuse.

MeSH terms

  • Adult
  • Affect / drug effects
  • Affective Symptoms / chemically induced*
  • Affective Symptoms / diagnosis
  • Affective Symptoms / psychology
  • Ambulatory Care
  • Amphetamine / adverse effects*
  • Amphetamine-Related Disorders / rehabilitation*
  • Central Nervous System Stimulants / adverse effects*
  • Cocaine / adverse effects*
  • Cocaine-Related Disorders / rehabilitation*
  • Comorbidity
  • Diagnosis, Dual (Psychiatry)
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Mental Disorders / diagnosis
  • Mental Disorders / psychology
  • Mental Disorders / rehabilitation*
  • Methamphetamine / adverse effects*
  • Middle Aged
  • Motivation*
  • Rhode Island
  • Substance Withdrawal Syndrome / diagnosis*
  • Substance Withdrawal Syndrome / psychology

Substances

  • Central Nervous System Stimulants
  • Methamphetamine
  • Amphetamine
  • Cocaine