TORCing up metabolic control in the brain

Cell Metab. 2008 May;7(5):357-8. doi: 10.1016/j.cmet.2008.04.006.

Abstract

Transducer of regulated CREB activity 2 (TORC2) is a coactivator of CREB and an important regulator of energy balance in mammals through control of gluconeogenesis in the liver. In this issue of Cell Metabolism, Wang and coworkers (2008) report an intriguing role for Drosophila TORC in the neuronal regulation of metabolism.

Publication types

  • Comment
  • Editorial

MeSH terms

  • Animals
  • Brain / metabolism*
  • Cyclic AMP Response Element-Binding Protein / metabolism*
  • Drosophila Proteins / metabolism*
  • Drosophila melanogaster
  • Gluconeogenesis / physiology
  • Phosphorylation
  • Transcription Factors / metabolism*

Substances

  • Cyclic AMP Response Element-Binding Protein
  • Drosophila Proteins
  • Transcription Factors