Immune-mediated pathways in chronic inflammatory arthritis

Best Pract Res Clin Rheumatol. 2008 Apr;22(2):221-38. doi: 10.1016/j.berh.2008.01.003.

Abstract

Rheumatoid arthritis (RA) is the prototype chronic inflammatory arthropathy; its precise aetiology is unknown. Over recent years, a number of crucial advances in our understanding of the disease have had a major impact on the treatment of patients with RA.

Publication types

  • Review

MeSH terms

  • Animals
  • Arthritis, Rheumatoid / genetics
  • Arthritis, Rheumatoid / immunology*
  • Arthritis, Rheumatoid / pathology
  • Autoimmunity / immunology
  • B-Lymphocytes / physiology
  • Chemokines / immunology
  • Dendritic Cells / immunology
  • Humans
  • Inflammation / immunology
  • Synovial Membrane / immunology
  • T-Lymphocyte Subsets / immunology
  • Toll-Like Receptors / immunology

Substances

  • Chemokines
  • Toll-Like Receptors