Approximately 13% of physician visits are for medically unexplained physical symptoms (MUPS), and up to 25% of patients report MUPS during visits to the doctor. Most of these patients' symptoms abate. But approximately 5% of patients are convinced they have a serious disease, although no problem can be diagnosed; these individuals are considered to be individuals with hypochondria. Estimates indicate they consume at least 10% of health care dollars and frustrate health care professionals. Treatment is possible, but paradoxical in nature. Clinicians must accept that the patient's concerns are real, and respect the patient's psychological defenses.