Abstract
Silver loaded zeolite (Ag-Z) was previously found to have effective bactericidal activity against Escherichia coli. To understand the mechanisms of bactericidal activity of Ag-Z, role of light irradiation was focused and investigated in this study. In this study, we focused on light irradiation. Antibacterial assay and spectroscopic study revealed that light irradiation enabled Ag-Z to reduce dioxygen to form a reactive oxygen species, which led to bactericidal activity. These results indicate that the onset of bactericidal activity can be controlled by light irradiation.
MeSH terms
-
Anti-Bacterial Agents / chemistry
-
Anti-Bacterial Agents / pharmacology*
-
Anti-Bacterial Agents / radiation effects*
-
Bacteria / drug effects*
-
Bacteria / enzymology
-
Bacteria / radiation effects*
-
Colony Count, Microbial
-
Cytochromes c / metabolism
-
Electron Spin Resonance Spectroscopy
-
Escherichia coli / drug effects
-
Escherichia coli / radiation effects
-
Light
-
Oxygen / chemistry
-
Oxygen / radiation effects
-
Reactive Oxygen Species / metabolism
-
Silver / chemistry
-
Silver / pharmacology*
-
Silver / radiation effects*
-
Spectrophotometry, Ultraviolet
-
Zeolites / chemistry
-
Zeolites / pharmacology*
-
Zeolites / radiation effects*
Substances
-
Anti-Bacterial Agents
-
Reactive Oxygen Species
-
Zeolites
-
Silver
-
Cytochromes c
-
Oxygen