Mitochondrial DNA population data of HV1 and HV2 sequences from Japanese individuals

Kazumasa Sekiguchi; Kazuhiko Imaizumi; Koji Fujii; Natsuko Mizuno; Yoshinori Ogawa; Tomoko Akutsu; Hiroaki Nakahara; Tetsushi Kitayama; Kentaro Kasai

doi:10.1016/j.legalmed.2008.02.002

Mitochondrial DNA population data of HV1 and HV2 sequences from Japanese individuals

Leg Med (Tokyo). 2008 Sep;10(5):284-6. doi: 10.1016/j.legalmed.2008.02.002. Epub 2008 Apr 28.

Authors

Kazumasa Sekiguchi¹, Kazuhiko Imaizumi, Koji Fujii, Natsuko Mizuno, Yoshinori Ogawa, Tomoko Akutsu, Hiroaki Nakahara, Tetsushi Kitayama, Kentaro Kasai

Affiliation

¹ National Research Institute of Police Science, Fourth Biology Section, 6-3-1 Kashiwanoha, Kashiwa-shi, Chiba 277-0882, Japan. kazumasa@nrips.go.jp

PMID: 18442943
DOI: 10.1016/j.legalmed.2008.02.002

Abstract

Mitochondrial DNA sequences of the hypervariable regions HV1 and HV2 were determined for 1204 unrelated Japanese individuals. A total of 741 different mtDNA haplotypes were found, 157 of which were seen in multiple individuals. Twenty-seven of these individuals showed point heteroplasmy. The most frequent haplotype (16223T-16362C-73G-263G-315.1C) was found in 31 individuals and the second most frequent haplotypes (16129A-16223T- 16362C-73G-152C-263G-309.1C-315.1C) was found in 24 individuals. The haplotypes diversity and random match probability were calculated to be 0.9969 and 0.0040, respectively.

MeSH terms

Asian People / genetics
Complementarity Determining Regions / genetics*
DNA Fingerprinting
DNA, Mitochondrial / genetics*
Genetics, Population*
Haplotypes*
Humans
Japan
Polymerase Chain Reaction
Sequence Analysis, DNA

Substances

Complementarity Determining Regions
DNA, Mitochondrial