Cationic iridium(III) complexes for phosphorescence staining in the cytoplasm of living cells

Chem Commun (Camb). 2008 May 14:(18):2115-7. doi: 10.1039/b800939b. Epub 2008 Feb 27.

Abstract

Two cationic iridium(III) complexes with bright green and red emissions were demonstrated as phosphorescent dyes for living cell imaging. In particular, their exclusive staining in cytoplasm, low cytotoxicity and reduced photobleaching, as well as cell membrane permeability, make the two complexes promising candidates for the design of specific bioimaging agents.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cations / chemistry
  • Cytoplasm / chemistry*
  • HeLa Cells
  • Humans
  • Iridium / chemistry*
  • Luminescence
  • Luminescent Agents / chemistry*
  • Luminescent Measurements / methods
  • Microscopy, Fluorescence
  • Molecular Structure
  • Organometallic Compounds / chemistry*
  • Photochemistry
  • Staining and Labeling

Substances

  • Cations
  • Luminescent Agents
  • Organometallic Compounds
  • Iridium