Synthesis of 1,5-anhydrohexitol building blocks for oligonucleotide synthesis

Curr Protoc Nucleic Acid Chem. 2003 Nov:Chapter 1:Unit 1.9. doi: 10.1002/0471142700.nc0109s14.

Abstract

This unit describes in detail, the optimized preparations of 1,5-anhydrohexitol and the 1,5-anhydrohexitol building blocks for oligonucleotide synthesis (hG, hA, hC, hT).

Publication types

  • Review

MeSH terms

  • Clinical Laboratory Techniques
  • Hexosephosphates / chemical synthesis*
  • Hexosephosphates / chemistry
  • Models, Biological
  • Oligonucleotides / chemical synthesis*
  • Sugar Alcohols / chemical synthesis*

Substances

  • Hexosephosphates
  • Oligonucleotides
  • Sugar Alcohols