Antioxidative compounds from Quercus salicina Blume stem

Arch Pharm Res. 2008 Mar;31(3):274-8. doi: 10.1007/s12272-001-1152-2. Epub 2008 Apr 13.

Abstract

The chromatographic separation of MeOH extract from the Quercus salicina Blume Stem led to the isolation of five phenolic compounds. Using spectroscopic methods, the structures of these compounds were determined as D-threo-guaiacylglycerol 8-O-beta-D-(6'-O-galloyl)glucopyranoside (1), 9-methoxy-D-threo-guaiacylglycerol 8-O-beta-D-(6'-O-galloyl)glucopyranoside (2), 6''-O-galloyl salidroside (3), methyl gallate (4), quercetin (5). We measured radical scavenging activity with the DPPH method and the anti-lipid peroxidative efficacy on human LDL with TBARS assay, with the result that all these compounds exhibited the antioxidative activity.

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology*
  • Biphenyl Compounds
  • Chromatography
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification
  • Free Radical Scavengers / pharmacology*
  • Gallic Acid / analogs & derivatives
  • Gallic Acid / pharmacology
  • Glucosides / pharmacology
  • Glycerol / analogs & derivatives
  • Glycerol / pharmacology
  • Humans
  • Lipid Peroxidation / drug effects*
  • Lipoproteins, LDL / metabolism
  • Magnetic Resonance Spectroscopy
  • Picrates / chemistry
  • Plant Stems
  • Quercetin / pharmacology
  • Quercus* / chemistry
  • Thiobarbituric Acid Reactive Substances / metabolism

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Free Radical Scavengers
  • Glucosides
  • Lipoproteins, LDL
  • Picrates
  • Thiobarbituric Acid Reactive Substances
  • oxidized low density lipoprotein
  • methyl gallate
  • Gallic Acid
  • Quercetin
  • 1,1-diphenyl-2-picrylhydrazyl
  • Glycerol