Cholesterol seco-sterol-induced aggregation of methylated amyloid-beta peptides--insights into aldehyde-initiated fibrillization of amyloid-beta

Angew Chem Int Ed Engl. 2008;47(21):3919-22. doi: 10.1002/anie.200705922.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alzheimer Disease / etiology
  • Amino Acid Sequence
  • Amyloid beta-Peptides / chemical synthesis*
  • Amyloid beta-Peptides / chemistry*
  • Binding Sites
  • Cholesterol / analogs & derivatives*
  • Cholesterol / chemistry
  • Kinetics
  • Methylation
  • Molecular Conformation
  • Molecular Sequence Data
  • Particle Size
  • Peptide Fragments / chemistry
  • Protein Folding
  • Time Factors

Substances

  • Amyloid beta-Peptides
  • Peptide Fragments
  • amyloid beta-protein (1-40)
  • atheronal-B
  • Cholesterol