Abstract
A new prenylated dihydrochalcone, 2',4'-dihydroxy-4-methoxy-3'-prenyldihydrochalcone (1), along with two known compounds, 2',4',4-trihydroxy-3'-prenylchalcone (2) and 2',4-dihydroxy-3',4'-(2,2-dimethylchromene)chalcone (3) were isolated from the leaves of Artocarpus lowii. The structures of 1-3 were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compounds 1-3 showed strong free radical scavenging activity towards 2,2-diphenyl-1-picrylhydrazyl (DPPH) measured by electron spin resonance (ESR) spectrometry.
MeSH terms
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Artocarpus / chemistry*
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Chalcones / chemistry
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Chalcones / isolation & purification
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Chalcones / pharmacology*
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Electron Spin Resonance Spectroscopy
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Free Radical Scavengers / chemistry
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Free Radical Scavengers / isolation & purification
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Free Radical Scavengers / pharmacology
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Free Radicals / metabolism
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Plant Extracts / chemistry
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Plant Extracts / isolation & purification
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Plant Extracts / pharmacology*
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Plant Leaves
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Spectrum Analysis
Substances
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2',4',4-trihydroxy-3'-prenylchalcone
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2',4'-dihydroxy-4-methoxy-3'-prenyldihydrochalcone
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2',4-dihydroxy-3',4'-(2,2-dimethylchromene)chalcone
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Chalcones
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Free Radical Scavengers
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Free Radicals
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Plant Extracts