Rhodium-catalyzed borylative cyclization of 2-alkynylaryl isocyanates with bis(pinacolato)diboron

Tomoya Miura; Yusuke Takahashi; Masahiro Murakami

doi:10.1021/ol800380t

Rhodium-catalyzed borylative cyclization of 2-alkynylaryl isocyanates with bis(pinacolato)diboron

Org Lett. 2008 May 1;10(9):1743-5. doi: 10.1021/ol800380t. Epub 2008 Apr 11.

Authors

Tomoya Miura¹, Yusuke Takahashi, Masahiro Murakami

Affiliation

¹ Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Japan.

PMID: 18402456
DOI: 10.1021/ol800380t

Abstract

2-alkynylaryl isocyanates reacted with bis(pinacolato)diboron in the presence of a cationic rhodium(I) catalyst to produce borylated 3-alkylideneoxindoles stereoselectively. The carbon-boron linkage formed was further transformed via reactions such as a cross-coupling and a halogenation reaction.