Abstract
An efficient and easy-to-execute single microbead SELEX approach is developed to generate high affinity ssDNA aptamers against botulinum neurotoxin.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Amino Acid Sequence
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Aptamers, Nucleotide / chemical synthesis*
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Aptamers, Nucleotide / chemistry
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Aptamers, Nucleotide / pharmacology*
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Botulinum Toxins / antagonists & inhibitors*
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Botulinum Toxins / chemistry
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DNA, Single-Stranded / chemical synthesis*
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DNA, Single-Stranded / chemistry
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DNA, Single-Stranded / pharmacology*
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Molecular Sequence Data
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Neurotoxins / antagonists & inhibitors*
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Neurotoxins / chemistry
Substances
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Aptamers, Nucleotide
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DNA, Single-Stranded
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Neurotoxins
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Botulinum Toxins