[Application of BED-CEIA to estimate the human immunodeficiency virus prevalence among injecting drug users in Chongqing municipality]

Zhonghua Liu Xing Bing Xue Za Zhi. 2007 Nov;28(11):1077-80.
[Article in Chinese]

Abstract

Objective: To estimate the human immunodeficiency virus (HIV-1) prevalence of injecting drug users (IDUs) in Chongqing city.

Methods: To apply BED-capture enzyme immunoassay (CEIA) which was based on the principle of HIV-antibody varies as the disease progress, in order to estimate both the HIV incidence and prevalence of IDUs from two IDUs surveillance sites in Chongqing.

Results: During the research period, 4711 serum samples were tested by ELISA and 130 were HIV-1 positive, confirmed by Western blot. The prevalence of IDUs surveillance site A from 1999 to 2006 were 0.73%, 2.02%, 1.54%, 2.96% and 2.80%, and the incidence rates were 0.57%, 0.93%, 0,1.24% and 1.68% respectively. The prevalence of IDUs surveillance site B appeared to be 4.21%, 9.96%, 8.13%, and the incidence rates were 0.95%, 1.04% and 0.90% respectively, from 2004 to 2006.

Conclusion: Many of the IDUs HIV carriers in Chongqing had been infected for long time, and the incidence rates among them were steady, keeping at the same level for 1-2 years. Promotion on intervention for IDUs had produced certain effects but more attention still needs to be paid.

Publication types

  • English Abstract

MeSH terms

  • AIDS Serodiagnosis / methods*
  • China / epidemiology
  • Drug Users
  • HIV Antibodies / blood
  • HIV Infections / blood
  • HIV Infections / epidemiology*
  • HIV Seroprevalence
  • Humans
  • Immunoenzyme Techniques
  • Incidence
  • Population Surveillance
  • Prevalence
  • Substance Abuse, Intravenous / epidemiology
  • Substance Abuse, Intravenous / virology*
  • Urban Population / statistics & numerical data

Substances

  • HIV Antibodies