Dioxin may promote inflammation-related development of endometriosis

Fertil Steril. 2008 May;89(5 Suppl):1287-98. doi: 10.1016/j.fertnstert.2008.02.102. Epub 2008 Apr 18.

Abstract

Laboratory and population-based studies suggest that exposure to environmental toxicants may be one of several triggers for the development of endometriosis. We discuss evidence that modulation of the endometrial endocrine-immune interface could mechanistically link toxicant exposure to the development of this disease.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Dioxins / toxicity*
  • Disease Models, Animal
  • Endometriosis / chemically induced*
  • Endometriosis / pathology
  • Endometriosis / physiopathology
  • Endometrium / physiology
  • Environmental Exposure / adverse effects
  • Female
  • Humans
  • Inflammation / chemically induced*
  • Models, Biological

Substances

  • Dioxins