Abstract
The methanol extract of kiwifruit leaf suppressed the postprandial blood glucose level after an oral administration of soluble starch or sucrose in mice. The mechanism of action is proposed to be due to the alpha-amylase-inhibiting activity in the 90% aqueous methanol fraction and alpha-glucosidase-inhibiting activity in the n-buthanol fraction, based on the results of in vitro experiments.
MeSH terms
-
Actinidia / chemistry*
-
Animals
-
Blood Glucose / metabolism
-
Glycoside Hydrolase Inhibitors
-
Hyperglycemia / drug therapy
-
Hyperglycemia / metabolism*
-
Inhibitory Concentration 50
-
Mice
-
Plant Extracts / pharmacology*
-
Plant Extracts / therapeutic use
-
Plant Leaves / chemistry*
-
Starch / pharmacology
-
Sucrose / pharmacology
-
alpha-Amylases / antagonists & inhibitors
-
alpha-Amylases / metabolism
-
alpha-Glucosidases / metabolism
Substances
-
Blood Glucose
-
Glycoside Hydrolase Inhibitors
-
Plant Extracts
-
Sucrose
-
Starch
-
alpha-Amylases
-
alpha-Glucosidases