Abstract
A concise, stereocontrolled synthesis of (+)-polyoxamic acid was achieved. Starting from trans-oxazoline as a chiral building block, the key step involves diastereoselective oxazine formation catalyzed by palladium(0).
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Amino Acids / chemical synthesis*
-
Amino Acids / chemistry
-
Molecular Conformation
-
Oxazines / chemical synthesis*
-
Oxazines / chemistry
-
Stereoisomerism
-
Sugar Acids / chemical synthesis*
-
Sugar Acids / chemistry
Substances
-
Amino Acids
-
Oxazines
-
Sugar Acids
-
polyoxamic acid