Abstract
N,N'-Diarylureas have been shown to efficiently catalyse sulfonium ylide-mediated aldehyde epoxidation reactions for the first time. These processes are of broad scope and can be coupled with a subsequent Cu(II) ion-catalysed Meinwald rearrangement to give an efficient and convenient protocol for aldehyde homologation without intermediate purification.
MeSH terms
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Aldehydes / chemistry*
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Catalysis
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Epoxy Compounds / chemical synthesis*
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Epoxy Compounds / chemistry
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Molecular Structure
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Sodium Hydroxide / chemistry
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Stereoisomerism
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Sulfonium Compounds / chemistry*
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Urea / analogs & derivatives*
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Urea / chemistry*
Substances
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Aldehydes
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Epoxy Compounds
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Sulfonium Compounds
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Sodium Hydroxide
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trimethylsulfonium
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Urea