Ground water budget analysis in arid basins is substantially aided by integrated use of numerical models and environmental isotopes. Spatial variability of recharge, storage of water of both modern and pluvial age, and complex three-dimensional flow processes in these basins provide challenges to the development of a good conceptual model. Ground water age dating and mixing analysis with isotopic tracers complement standard hydrogeologic data that are collected and processed as an initial step in the development and calibration of a numerical model. Environmental isotopes can confirm or refute a priori assumptions of ground water flow, such as the general assumption that natural recharge occurs primarily along mountains and mountain fronts. Isotopes also serve as powerful tools during postaudits of numerical models. Ground water models provide a means of developing ground water budgets for entire model domains or for smaller regions within the model domain. These ground water budgets can be used to evaluate the impacts of pumping and estimate the magnitude of capture in the form of induced recharge from streams, as well as quantify storage changes within the system. The coupled analyses of ground water budget analysis and isotope sampling and analysis provide a means to confirm, refute, or modify conceptual models of ground water flow.