In the context of the use of carbohydrates obtained from agricultural crops, the search for amphiphilic derivatives is one of the most developed aspects. Indeed, due to the high polarity and the functional richness of sugars, many different structures can be targeted, with a wide range of physicochemical properties, either for large scale products of industrial interest, or for fine applications at the chemistry-biology interface. Among carbohydrates arising from agricultural resources, sucrose is especially interesting because of its very large production scale in the world (ca. 160Mt/year, ca. 20Mt/year of which in the European Community). Here, we describe the research accomplished in our group dealing with the synthesis and the study of the properties of amphiphilic derivatives prepared from sucrose as well as from another very available disaccharide, isomaltulose.