Objective: To evaluate the status of medical therapy in the revascularized coronary artery disease (CAD) patients treated in Anzhen Hospital.
Methods: 2048 CAD patients who received revascularization during July 2003 to June 2004 were registered in DESIRE database. The methods of revascularization [percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG)] and use of medicines [aspirin, betablocker (BB), statins, angiotension converting enzyme inhibitor (ACEI) etc] during hospitalization and during the follow-up were recorded. The patients were followed up for a mean time of 587 +/- 127 days.
Results: The prescription rates of aspirin, BB, statins, and ACEI were 93.9%, 88.9%, 67.7%, and 62.9% respectively. 58.9% of the patients used combined aspirin, BB, and statins; and 39.7% of the patients used combined aspirin, BB, statins, and ACEI. The prescription rates of these drugs was all significantly higher in the PCI group than in the CABG group (all P < 0.001). The prescription rates of these drugs during follow-up were 90.8%, 57.4%, 43.0%, and 24.5% respectively, all significantly lower than those during hospitalization (all P < 0.001). The prescription rates of these medicines were all significantly higher in Beijing compared with in the areas other than Beijing (all P < 0.001).
Conclusion: The CAD patients who received revascularization show a high proportion of using secondary prevention drugs during hospitalization, and the prescription rates of these drugs decrease significantly during follow-up, especially in those who received CABG and who live outside Beijing.